On the InterSystems Developer Community, you can find an example article series on modern web app development. The series starts from scratch and should allow anyone without prior knowledge to install and test a small web app with modern JavaScript technologies.
It shows you step-by-step how to install a Node.js development environment first and create a small React app connecting to Caché. At the front-end, the example is using React and different kinds of back-ends integrated with Caché are covered in the example.
Don’t forget to check it out and give your feedback!
Caché User Group (CUG) Benelux blog 